143 is unsecured IMAP, you could try 993 with SSL.
2525 would be for SMTP, sending mail... Port 25 is the "legacy" port for that (again, unsecured), and is very often blocked by ISPs to prevent the spread of malware (or so they think...)
I would say, try port 465 with SSL too.
However, a lot will depend on your mail provider -- if this is your ISP's mail system, it's entirely possible that it's not accessible at all when you're not connected to their network (using home WiFi).
This would be a really strange setup, but I've seen it.
Finally, try the latest dev build - it has a way under account setup to specify different outgoing mail server settings when on WiFi.