Acknowledging delivery is a big problem in the world full of SPAM, as it is one of the channels of collecting/confirming existing accounts.
I've heard this many times: "I've just set up a brand new e-mail account john@{server}. I haven't sent any message from it and have not shared this address with anybody, but I started receiving SPAM."
FWIW: I've just set up a new server (that includes e-mail capabilities for the users), and purposely set all defaults to avoid generating or requesting any acknowledgments (delivery, reading, ... ).